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Dr. Samuel "Sam" Abrams is the Head of Neurosurgery at Gaffney Chicago Medical Center. He is portrayed by Brennan Brown.


Abrams has an abrasive, no-nonsense personality and way of communicating with his colleagues and patients. He often criticizes others' decisions as rash or based too much on emotion.

Season Five

Never Going Back to Normal

Sam evaluates Natalie's neurological function when she wakes up with a traumatic brain injury sustained while being attacked in Will's car by Tim Burke. In a rare moment of affection, he tells her that he is happy that she is doing well. He proposes performing brain surgery on a young boy with an apparent tumor, but he is talked out of it by Ethan, who believes the abnormality is brought on by hypothyroidism and doesn't need surgery.

The Ground Shifts Beneath Us

Sam is believed to have been in a plane crash upon returning from a conference in Honolulu. When a patient who is severely burned beyond recognition is brought into the hospital, his colleagues fear and assume that it is him. His wife Michelle, perceived by many as a "trophy wife" because of her young age and good looks, pushes to take Abrams off life support, citing that he would not want to live this way. The doctors delay the decision as long as possible, as they believe Michelle just wants to cash in on his life insurance.

Towards the end of the episode, the real Dr. Abrams returns to the hospital in casual Hawaiian attire, informing everyone that he had decided to stay in Hawaii a few more days, and therefore he was not on the plane that crashed. The burned patient turns out to be a sales representative who was also at the conference. He admonishes his colleagues for not having taken his presumed body off life support earlier, saying that Michelle was absolutely correct to convey that he would not want to be kept alive artificially. He also reveals that Michelle is not the "trophy wife" everyone assumes her to be, and that he is actually the "trophy husband", Michelle having become a millionaire through her dietary supplements company.


Season 1
Derailed iNo Fallback Mistaken Malignant
Bound Saints Reunion Choices Clarity
Intervention Guilty Us Hearts Inheritance
Disorder Withdrawal Timing
Season 2
Soul Care Win Loss Natural History Brother's Keeper Extreme Measures
Alternative Medicine Inherent Bias Free Will Uncharted Territory Heart Matters
Graveyard Shift Mirror Mirror Theseus' Ship Cold Front Lose Yourself
Prisoner's Dilemma Monday Mourning Lesson Learned Ctrl Alt Generation Gap
Deliver Us White Butterflies Love Hurts
Season 3
Speak Your Truth Nothing to Fear Trust Your Gut Naughty or Nice Mountains and Molehills
Ties That Bind Over Troubled Water Lemons and Lemonade On Shaky Ground Down By Law
Folie à Deux Born This Way Best Laid Plans Lock It Down Devil in Disguise
An Inconvenient Truth The Parent Trap This Is Now Crisis of Confidence The Tipping Point
Season 4
Be My Better Half When to Let Go Heavy Is the Head Backed Against the Wall What You Don't Know
Lesser of Two Evils The Poison Inside Us Play by My Rules Death Do Us Part All the Lonely People
Who Can You Trust The Things We Do Ghosts in the Attic Can't Unring That Bell We Hold These Truths
Old Flames, New Sparks The Space Between Us Tell Me the Truth Never Let You Go More Harm Than Good
Forever Hold Your Peace With a Brave Heart
Season 5
Never Going Back to Normal We're Lost in the Dark In the Valley of the Shadows Infection, Part II Got a Friend in Me
It's All in the Family Who Knows What Tomorrow Brings Too Close to the Sun I Can’t Imagine the Future Guess It Doesn't Matter Anymore
The Ground Shifts Beneath Us Leave the Choice to Solomon Pain Is for the Living It May Not Be Forever I Will Do No Harm
Who Should Be the Judge The Ghosts of the Past In the Name of Love Just a River in Egypt A Needle in the Heart
Season 6
When Did We Begin to Change Those Things Hidden in Plain Sight Do You Know the Way Home? In Search of Forgiveness, Not Permission When Your Heart Rules Your Head
Don't Want to Face This Now Better Is the Enemy of Good Fathers and Mothers, Daughters and Sons For the Want of a Nail So Many Things We've Kept Buried
Letting Go Only to Come Together Some Things Are Worth the Risk What a Tangled Web We Weave A Red Pill, a Blue Pill Stories, Secrets, Half-Truths and Lies
I Will Come to Save You
Season 7
You Can't Always Trust What You See To Lean In, or To Let Go Be the Change You Want to See Status Quo, aka the Mess We're In Change Is a Tough Pill to Swallow
When You're a Hammer, Everything's a Nail A Square Peg in a Round Hole Just as a Snake Sheds Its Skin Secret Santa Has a Gift For You No Good Deed Goes Unpunished... in Chicago
The Things We Thought We Left Behind What You Don't Know Can't Hurt You Reality Leaves a Lot to the Imagination All The Things That Could Have Been Things Meant to Be Bent Not Broken
May Your Choices Reflect Hope, Not Fear If You Love Someone, Set Them Free Judge Not, For You Will Be Judged Like a Phoenix Rising from the Ashes End of the Day, Anything Can Happen
Lying Doesn't Protect You from the Truth And Now We Come to the End