Chicago Med Wiki
"Infection: Part II"
Season 5, Episode 04
Infection- Part II (1).jpeg
Air date October 16, 2019
Story by Dick Wolf & Derek Haas
Teleplay by Diane Frolov & Andrew Schneider
Directed by Michael Pressman
Runtime 41 minutes
Episode Guide
"In the Valley of the Shadows"
"Got a Friend in Me"

Infection: Part II is the fourth episode of season 5 of Chicago Med. It is part 2 of a crossover with Chicago Fire and Chicago P.D.


The 3-episode arc starts with Chicago Fire season 8, episode 4 (Infection: Part I), continues with Infection: Part II, and ends with Chicago P.D. season 7, episode 4 (Infection: Part III).


The entire population of an apartment complex is forced into quarantine when multiple cases of the flesh-eating bacteria are discovered. The Chicago P.D. Intelligence Unit chases a lead that could point to a case of bioterrorism, while multiple patients succumb to the disease. Dr. Halstead works closely with a representative from the CDC and doctors from the involved university lab, putting him dangerously close to the suspect. Meanwhile, Sharon Goodwin deals with the press.


Main Cast


The episode highlights multiple aspects of a mass panic induced by an infectious disease outbreak:

  • The way panic spreads throughout a population as news spreads;
  • Sensationalist coverage by news media;
  • Conspiracy theories;
  • People with immigrant backgrounds being blamed for the spread of disease;
  • Tensions between public health and financial and PR considerations.

Medical Cases

Many patients are surgically treated in an attempt to remove infected tissue, with multiple patients succumbing. One patient is saved by amputating an infected arm.

Notes and Trivia

  • The samples of the flesh-eating bacteria are said to require the highest level (level 4) of biomedical security, but the characters are seen handling them without any protective gear. Similarly, Dr. Marcel is seen wiping his face with a hand covered in blood from a patient who has just died of the bacteria.