|"I Will Do No Harm"|
|Season 5, Episode 15|
|Air date||February 26, 2020|
|Written by||Joseph Sousa & Danny Weiss|
|Directed by||Vanessa Parise|
"It May Not Be Forever"
"Who Should Be the Judge"
Dr. Charles and Dr. Manning treat a patient who is fully invested in pretending to be someone other than himself. Noah begins to doubt his abilities as a doctor. Dr. Marcel and Dr. Choi are faced with a tough ethical decision. Dr. Halstead puts his faith in an addict.
- Brian Tee as Dr. Ethan Choi
- Marlyne Barrett as Maggie Lockwood
- Nick Gehlfuss as Dr. Will Halstead
- Oliver Platt as Dr. Daniel Charles
- S. Epatha Merkerson as Sharon Goodwin
- Torrey DeVitto as Dr. Natalie Manning
- Yaya DaCosta as Nurse April Sexton
- Dominic Rains as Dr. Crockett Marcel