|Do You Know the Way Home?|
|Season 6, Episode 3|
|Air date||January 13, 2021|
|Written by||Jeff Drayer & Gabriel L. Feinberg|
|Directed by||Mykelti Williamson|
"Those Things Hidden in Plain Sight"
In Search of Forgiveness, Not Permission
Dr. Halstead's eagerness to enroll a patient in his clinical trial puts him at odds with the patient's daughter. April, Dr. Charles and Dr. Choi identify a girl who went missing as a child. Dr. Marcel treats an acquaintance for a stab wound. Dr. Manning treats a patient with incoherent symptoms via video chat.
- Brian Tee as Dr. Ethan Choi
- Marlyne Barrett as Maggie Lockwood
- Nick Gehlfuss as Dr. Will Halstead
- Oliver Platt as Dr. Daniel Charles
- S. Epatha Merkerson as Sharon Goodwin
- Torrey DeVitto as Dr. Natalie Manning
- Yaya DaCosta as Nurse April Sexton
- Dominic Rains as Dr. Crockett Marcel
- Tehmina Sunny as Dr. Sabeena Virani
- Nate Santana as Dr. James Lanik
- Jill Abramovitz as Susan Charles
- Lorena Diaz as Nurse Doris
- Marie Tredway as Nurse Trini
- Elena Marisa Flores as Officer Rosado
- Caitlan Taylor as Paramedic Michelle
- Hannah James as Megan
- Keira Prinz as Kelly Bissett
- Wendy Mateo as Mari Esquivel
- Lynne Lipton as Ms. Webb
- Linda Reiter as Mrs. Bissett
- Ricardo Gutierrez as Ruben Esquivel
- Anthony Irons as Alvin Booker
- Thomas Adisi as George
This episode continues to highlight the difficulties associated with the coronavirus pandemic:
- Financial strain put on hospitals due to the large percentage of patients being treated for COVID-19 bringing in less revenue compared to other treatments;
- Patients having to be treated via video call because they are unable or too afraid to leave home for fear of contracting the virus.
- A man named Alvin Booker is discharged after having recovered from COVID-19;
- A young woman named Lisa is treated for a bacterial infection with IV antibiotics. After her suspicious behavior raises red flags, Dr. Charles, Dr. Choi and April find out she is actually a woman named Kelly Bissett who disappeared as a child;
- A man named Ruben Esquivel is treated for heart failure. After initial disagreement with the patient's daughter, Dr. Halstead enrolls him in his new clinical trial, and his condition improves;
- A paramedic named Megan is treated for a stab wound to the right flank;
- A woman with incoherent symptoms named Ms. Webb is treated via video call. After multiple calls she reveals that she is not actually suffering from any of the symptoms she mentioned and instead called the hospital because she felt lonely due to being isolated at home.
- This episode was intended to air on January 6 but was pushed back due to the storming of the United States Capitol. In Canada, the episode started to air but was replaced by a re-run of the previous episode halfway through;
- This episode was sponsored by Apple's FaceApp. Dr. Charles, Dr. Choi and April use the app to de-age a photo of Lisa, which allows them to identify her as Kelly Bissett.